Program | 2026 Frontier Symposium in Computational and Experimental Biophysics and Bioscience

Friday

November 6

08:30-08:50 Registration
08:50-09:00 Opening Remarks (Wonpil Im)
09:00-10:30
Session 1: AI-Driven Drug Discovery & Structural Modeling (Chair: Jaewoon Jung)

09:00-09:30

Woong-Hee Shin

Korea University

AI-aided structure-based drug discovery

09:30-10:00

Hojung Nam

Yonsei University

Generative AI and the Rise of New Drug Modalities

10:00-10:30

Jun Ohnuki

Institute for Molecular Science

Bridging Molecular Simulations and AlphaFold to Explore Conformational Changes in Proteins
10:30-11:00 Coffee Break
11:00-12:30
Session 2: Multiscale Simulation, Peptide Design & Biomaterials (Chair: Eiji Yamamoto)

11:00-11:30

Wenfei Li

Nanjing University

AI-powered multiscale simulations of protein molecules

11:30-12:00

Hee-Jung Choi

Seoul National University

Structure-guided design of peptide ligands with NPY receptor subtype selectivity

12:00-12:30

Eunji Lee

GIST

Self-Assembled Antifreeze Peptides: A Biomimetic Route to Cryopreservation
12:30-14:00 Lunch
14:00-15:30
Session 3: Cellular Interfaces & Whole-Cell Simulations (Chair: Wonpil Im)

14:00-14:30

Siwert Marrink

University of Groningen

Simulating whole cells with Martini

14:30-15:00

Miho Yanagisawa

The University of Tokyo

Lipid Membranes as Active Interfaces: From Molecular Organization to Cellular Mechanics

15:00-15:30

Misa Minegishi

Kyoto University

Technologies to understand cell–microenvironment interactions
15:30-16:00 Coffee Break
16:00-17:30
Session 4: Genome Architecture, Epigenetic Dynamics & Cellular Fluctuations (Chair: Chang Yun Son)

16:00-16:30

Jaeyoung Sung

Chung-Ang University

Fundamental principles and equations governing cellular signal propagation, adaptive gene expression, and biological condensate formation

16:30-17:00

Kai Huang

Shenzhen Bay Laboratory

Self-organized epigenetic signal processing in active chromatin

17:00-17:30

Risa Kawaguchi

The University of Tokyo

Epigenetic Landscape Dynamics Underlying Stochastic Cell and Individual Fate Determination
17:45-18:45 Poster Session
18:00-20:00Banquet

Saturday

November 7

09:00-10:30
Session 5: Biomolecular Condensates & Phase Separation (Chair: Cheng Tan)

09:00-09:30

Saehyun Choi

Ewha Womans University

Biomolecular Condensates for Regulation of RNA Equilibria and Signal Transduction

09:30-10:00

Min Ju Shon

POSTECH

Architectural Roles of Protein Condensates across DNA, Cytoskeletal, and Membrane Systems

10:00-10:30

Yi Wang

The Chinese University of Hong Kong

Small-molecule permeation and condensate-membrane interactions probed by molecular simulations
10:30-11:00 Coffee Break
11:00-12:30
Session 6: Computational Protein Design & Macromolecular Reconstitution (Chair: Takahiro Kosugi)

11:00-11:30

Gyu Rie Lee

KAIST

De novo protein design for chemical recognition and enzymatic catalysis

11:30-12:00

Lizhe Zhu

The Chinese University of Hong Kong, Shenzhen

Designing the Kinetics of Biomolecular Interactions

12:00-12:30

Yongchan Lee

Yokohama City University

Prediction-guided reconstitution of membrane protein complexes
12:30-14:00 Lunch (group photo)
14:00-15:30
Session 7: Multiscale Membrane Modeling & Biophysical Platforms (Chair: Yuji Sugita)

14:00-14:30

Song Yang

Fuzhou University

Developing Gō-Martini Methods for Membrane Protein Conformational Transitions and Lipid Interactions

14:30-15:00

Fabian Gruenewald

HITS / FIAS

Hybrid Polymer-Lipid Membranes as a Virtual Platform for Membrane Biology

15:00-15:30

Hee-Sun Han

University of Illinois Urbana-Champaign

Resolving Heterogeneous Biological Systems One Component at a Time: From Viral Evolution to Membrane Biophysics
15:30-16:00 Coffee Break
16:00-17:30
Session 8: Biosimulation Repositories & MD Data Bank (MDDB) (Chair: Chigusa Kobayashi)

16:00-16:30

Adam Hospital

IRB Barcelona

Molecular dynamics data bank. Current status of the European repository for biosimulation data

16:30-17:00

Genji Kurisu

Osaka University

Protein Data Bank: the single global archive for 3D macromolecular structure data

17:00-17:30

Yasuhiro Matsunaga

Saitama University

MDDB-AI Hub: An Evaluation Platform for Molecular Dynamics Surrogate Models
17:45-18:45 Poster Session

Sunday

November 8

09:00-09:30 Scientific Discussion
09:30-10:30
Session 9: Membrane Proteins & Biomolecular Dynamics (Chair: Yongchang Lee)

09:30-10:00

Ai Niitsu

RIKEN

Molecular dynamics simulations of membrane peptide binding and assembly toward rational design

10:00-10:30

Sandhya Premnath Tiwari

Institute for Protein Research, Osaka University

Analyzing Protein–Protein Coupled Motions to Understand the Conformational Dynamics of Protein Complexes
10:30-11:00 Coffee Break
11:00-12:00
Session 10: Multiscale Resolution, Enhanced Sampling & Protein Dynamics (Chair: Ai Shinobu)

11:00-11:30

Rakwoo Chang

University of Seoul

FM-ResXMD: Force-Matched Resolution Exchange Molecular Dynamics Simulation Methods for Enhanced Sampling of Ionic Liquids

11:30-12:00

Cheng Tan

RIKEN Center for Computational Science

From Coarse-Grained to Atomic Resolution: Multiscale Simulations Reveal How TDP-43 Condensates Are Regulated
12:00-12:10 Closing Remarks (Yuji Sugita)